The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase 3 AMPLITUDE trial: Niraparib (NIRA) and abiraterone acetate plus prednisone (AAP) for metastatic castration-sensitive prostate cancer (mCSPC) patients (pts) with alterations in homologous recombination repair (HRR) genes.
 
Gerhardt Attard
Honoraria - Astellas Pharma; Janssen; Janssen (I)
Consulting or Advisory Role - Abbott Laboratories; Amgen; Astellas Pharma; AstraZeneca; Bayer; Blue Earth Therapeutics; ESSA; Ferring; Janssen-Cilag; Medivation; Merck; Merck Serono; Millennium; Novartis; Novartis; Pfizer; Ventana Medical Systems; Veracyte; Veridex
Speakers' Bureau - Astellas Pharma; AstraZeneca; Ferring; Ipsen; Janssen; Sandoz; Sanofi; Takeda; Ventana Medical Systems
Research Funding - Astellas Pharma (Inst); Blue Earth Therapeutics; Janssen (Inst); Novartis; Veracyte
Patents, Royalties, Other Intellectual Property - I am on The ICR rewards to inventors list of abiraterone acetate.; listed as inventor on docetaxel predictive biomarker (Veracyte); listed as inventor on patent related to blood biomarkers (UCL, Cancer Research Horizons)
Travel, Accommodations, Expenses - Abbott Laboratories; Amgen; Arvinas; Astellas Pharma; Astellas Pharma (I); AstraZeneca; Bayer; Bristol Myers Squib (I); ESSA; Ferring; Janssen; Janssen (I); Medivation; Merck Serono; Novartis; Orion Clinical; Pfizer; Propella Therapeutics; Sanofi; Ventana Medical Systems
Other Relationship - Institute of Cancer Research
 
Neeraj Agarwal
Research Funding - Amgen (Inst); Arvinas (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Celldex (Inst); crispr therapeutics (Inst); Eisai (Inst); Exelixis (Inst); Genentech (Inst); Gilead Sciences (Inst); Immunomedics (Inst); Janssen (Inst); Lilly (Inst); Merck (Inst); Nektar (Inst); ORIC Pharmaceuticals (Inst); ORIC Pharmaceuticals (Inst); Pfizer (Inst); Takeda (Inst)
Travel, Accommodations, Expenses - Exelixis; Pfizer
 
Julie Graff
Research Funding - Curium Pharma (Inst); Janssen Oncology (Inst); Merck (Inst)
Patents, Royalties, Other Intellectual Property - Oncoresponse: Exceptional responders
 
Shahneen Sandhu
Honoraria - Abbvie (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Janssen (Inst); Merck (Inst); Merck Serono (Inst); Novartis (Inst); Skyline Diagnostics (Inst)
Consulting or Advisory Role - Abbvie (Inst); AstraZeneca (Inst); Bristol Myers Squibb (Inst); Merck Sharp and Dohme (Inst); Novartis (Inst); Roche/Genentech (Inst); Skyline Diagnostics (Inst)
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Endocyte/Advanced Accelerator Applications (Inst); Genentech/Roche (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Senhwa Biosciences (Inst)
(OPTIONAL) Uncompensated Relationships - AAA/Endocyte/Novartis (Inst)
 
Eleni Efstathiou
Honoraria - AstraZeneca; Bayer; Myovant Sciences; Pfizer; Sumitomo
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Johnson & Johnson; Merck; Pfizer; Tolmar
Research Funding - Astellas Pharma; AstraZeneca; Johnson & Johnson; Merck; Pfizer
 
Mustafa Özgüroglu
Honoraria - Astellas Pharma; Janssen Oncology (Inst); Novartis
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; MSD Oncology
Speakers' Bureau - AstraZeneca
Travel, Accommodations, Expenses - AstraZeneca
 
Andrea Pereira de Santana Gomes
Honoraria - Adium Pharma; Adium Pharma; Astellas Pharma; AstraZeneca; Bayer; Janssen Oncology
Consulting or Advisory Role - Bayer; Janssen Oncology
Speakers' Bureau - Astellas Pharma; AstraZeneca; Bayer; Janssen Oncology
Research Funding - AstraZeneca; Bayer; Janssen Oncology; MSD Oncology; Roche
Travel, Accommodations, Expenses - Janssen Oncology
 
Karina Vianna
Consulting or Advisory Role - Adium Pharma; AstraZeneca; Roche/Genentech
Speakers' Bureau - AstraZeneca; Bayer; BMS Brazil; GlaxoSmithKline; Knight Pharmaceuticals; Pfizer; Roche/Genentech; SERVIER
Research Funding - AstraZeneca (Inst); BeiGene (Inst); Bristol-Myers Squibb Brazil (Inst); Gilead Sciences (Inst); Incyte (Inst); Janssen Oncology (Inst); Lilly (Inst); MSD Oncology (Inst); Roche/Genentech (Inst); Seagen (Inst); SERVIER (Inst)
Travel, Accommodations, Expenses - AstraZeneca; MSD Oncology; Roche/Genentech
 
Hong Luo
No Relationships to Disclose
 
Heather Cheng
Consulting or Advisory Role - Janssen Oncology
Research Funding - Clovis Oncology (Inst); Janssen (Inst); Phosplatin Therapeutics (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - UpToDate
 
Won Kim
Employment - Johnson & Johnson/Janssen
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
 
Carly Varela
Employment - Johnson & Johnson/Janssen
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
 
Daneen Schaeffer
Employment - Johnson & Johnson/Janssen
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
Travel, Accommodations, Expenses - Johnson & Johnson/Janssen
 
Shiva Dibaj
Employment - Johnson & Johnson/Janssen
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
Patents, Royalties, Other Intellectual Property - I have been a part of the AKEEGA drug development
Travel, Accommodations, Expenses - Johnson & Johnson/Janssen
 
Susan Li
Employment - Janssen Research & Development, LLC, a Johnson & Johnson company
Stock and Other Ownership Interests - Janssen Research & Development, LLC, a Johnson & Johnson company
 
Fei Shen
Employment - Johnson & Johnson/Janssen
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
 
Suneel Dinkar Mundle
Employment - Janssen
Stock and Other Ownership Interests - Johnson & Johnson
 
David Olmos
Stock and Other Ownership Interests - VDG diagnostics
Honoraria - Bayer; Janssen
Consulting or Advisory Role - AstraZeneca; Bayer; Janssen; MSD Oncology; Pfizer
Research Funding - Johnson & Johnson/Janssen (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - AstraZeneca Spain; Bayer; Janssen
 
Kim Chi
Honoraria - Amgen; Astellas Pharma; AstraZeneca; Bayer; BMS GmbH & Co. KG; BMS GmbH & Co. KG; Janssen; Merck; Novartis; Pfizer; POINT Biopharma; Roche
Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bayer; BMS GmbH & Co. KG; Janssen; Merck; POINT Biopharma; Roche
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); ESSA (Inst); Janssen (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst); Sanofi (Inst)
 
Dana Rathkopf
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb/Celgene; Genentech; Janssen; Myovant Sciences; Novartis; Promontory
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb/Celgene (Inst); Genentech/Roche (Inst); Janssen Oncology (Inst); Novartis (Inst); Promontory Therapeutics (Inst)
 
on behalf of the AMPLITUDE Investigators
No Relationships to Disclose