The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Inhaled KB707, a novel HSV-based immunotherapy, as a monotherapy in patients with advanced solid tumor malignancies affecting the lungs: Efficacy and safety results from a phase 1/2 study.
 
Wen Wee Ma
Honoraria - Ipsen; Taiho Oncology
Consulting or Advisory Role - Kodikaz Therapeutic Solutions
Research Funding - 1ST Biotherapeutics (Inst); Actuate Therapeutics (Inst); Athenex (Inst); BioMed Valley Discoveries (Inst); Bristol-Myers Squibb (Inst); Cardiff Oncology (Inst); CUE Biopharma (Inst); Elucida Oncology (Inst); Genentech (Inst); GI Innovation (Inst); Ipsen (Inst); Jacobio (Inst); Krystal Biotech (Inst); Lilly (Inst); Merus (Inst); Repare Therapeutics (Inst); Sun Pharma (Inst); Takeda (Inst)
 
Meredith McKean
Consulting or Advisory Role - Castle Biosciences (Inst); IQVIA (Inst); Merck (Inst); Moderna Therapeutics (Inst); Pfizer (Inst)
Research Funding - AADi (Inst); Alpine Immune Sciences (Inst); Arcus Biosciences (Inst); Arvinas (Inst); Ascentage Pharma Group (Inst); ASCO (Inst); Astellas Pharma (Inst); Aulos Bioscience (Inst); Bayer (Inst); Bicycle Therapeutics (Inst); BioMed Valley Discoveries (Inst); BioNTech (Inst); Bristol-Myers Squibb (Inst); C4 Therapeutics (Inst); Dragonfly Therapeutics (Inst); EMD Serono (Inst); Epizyme (Inst); Erasca, Inc (Inst); Exelixis (Inst); Foghorn Therapeutics (Inst); G1 Therapeutics (Inst); Genentech (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); IDEAYA Biosciences (Inst); Ikena Oncology (Inst); Immvira (Inst); Infinity Pharmaceuticals (Inst); Jacobio (Inst); Kechow Pharma (Inst); Kezar Life Sciences (Inst); Kinnate Biopharma (Inst); MedImmune (Inst); Mereo BioPharma (Inst); Metabomed (Inst); Moderna Therapeutics (Inst); NBE Therapeutics (Inst); Nektar (Inst); Novartis (Inst); NucMito Pharmaceuticals (Inst); OncoC4 (Inst); Oncorus (Inst); OnKure (Inst); PACT Pharma (Inst); Pfizer (Inst); Plexxikon (Inst); Poseida (Inst); Prelude Therapeutics (Inst); Pyramid Biosciences (Inst); Regeneron (Inst); Sapience Therapeutics (Inst); Scholar Rock (Inst); Seagen (Inst); Synthorx (Inst); Tempest Therapeutics (Inst); TeneoBio (Inst); Tizona Therapeutics, Inc. (Inst); Tmunity Therapeutics, Inc. (Inst); Top Alliance BioScience (Inst); Xilio Therapeutics (Inst)
 
Liza Villaruz
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb/Celgene; Daiichi Sankyo/Astra Zeneca; EMD Serono; Gilead Sciences; Janssen Oncology; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Sanofi/Regeneron; Takeda
Research Funding - AstraZeneca (Inst); BioAtla (Inst); BMS (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Jazz Pharmaceuticals (Inst); Lilly (Inst); Merck (Inst); Regeneron (Inst)
 
Daniel Johnson
Consulting or Advisory Role - Amgen; Daiichi Sankyo/Lilly; Nectin Therapeutics; Signalexis
Speakers' Bureau - AstraZeneca/MedImmune; Bristol-Myers Squibb/Pfizer; Merck
 
Mateusz Opyrchal
No Relationships to Disclose
 
Justin Moser
Honoraria - Caris Life Sciences; Daiichi Sankyo/Lilly; TGen
Consulting or Advisory Role - Adagene; Amunix; Boxer Capitol; Bristol Myers Squibb Foundation; Genome Insight; Imaging Endpoints; Incyte; IQvia; Novotech; Oberland Capital; Red Arrow Therapeutics; Thirona Biosciences; Werewolf Therapeutics (Inst)
Speakers' Bureau - Caris Life Sciences; Castle Biosciences; Immunocore
Research Funding - Adaptimmune (Inst); Agenus (Inst); Alpine Immune Sciences (Inst); Amgen (Inst); BioEclipse Therapeutics (Inst); Fate Therapeutics (Inst); Fujifilm (Inst); Genentech (Inst); IDEAYA Biosciences (Inst); ImmuneSensor Therapeutics (Inst); Iovance Biotherapeutics (Inst); Istari Oncology (Inst); Nektar (Inst); Novocure (Inst); Repertoire Immune Medicines (Inst); Rubius Therapeutics (Inst); Senhwa Biosciences (Inst); Simcha Therapeutics (Inst); Storm Therapeutics (Inst); Synthorx (Inst); T-Scan Therapeutics (Inst); Trishula Therapeutics (Inst); University of Arizona (Inst); Werewolf Therapeutics (Inst); Y-mAbs Therapeutics (Inst)
Other Relationship - Caris Life Sciences
 
Kristin Gabor
Employment - Krystal Biotech (I)
Stock and Other Ownership Interests - Krystal Biotech
 
Suma Krishnan
Employment - Krystal Biotech
Leadership - Krystal Biotech; Krystal Biotech (I)
Stock and Other Ownership Interests - Krystal Biotech; Krystal Biotech (I)
 
David Chien
Employment - Krystal Biotech, Inc.
Stock and Other Ownership Interests - Abbvie; Amgen; Krystal Biotech, Inc.; Nektar