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A phase 1a/1b study to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of IMGS-001 in patients with relapsed or refractory advanced solid tumors. |
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Employment - MD Anderson Cancer Center |
Stock and Other Ownership Interests - crossbridge Bio; MolecularMatch; OncoResponse; Telperian |
Consulting or Advisory Role - Amgen; Bayer; BeiGene; Bristol Myers Squibb Company; Janssen; Mirati Therapeutics; Sanofi and Genzyme US Companies |
Research Funding - Abbvie (Inst); Amgen (Inst); Bayer (Inst); Bristol Myers Squibb (Inst); Deciphera Pharmaceuticals Inc. (Inst); Genentech (Inst); Incyte (Inst); Merck Sharp & Dohme LLC (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst) |
Travel, Accommodations, Expenses - AACR; ASCO; Bayer Schering Pharma; CLCC; Genmab; Society for Immunotherapy of Cancer; Telperian |
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No Relationships to Disclose |
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Employment - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Research Funding - ImmunoGenesis |
Travel, Accommodations, Expenses - ImmunoGenesis |
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Employment - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Research Funding - ImmunoGenesis |
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Employment - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Research Funding - ImmunoGenesis |
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Employment - ImmunoGenesis |
Leadership - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Honoraria - ImmunoGenesis |
Consulting or Advisory Role - ImmunoGenesis |
Patents, Royalties, Other Intellectual Property - ImmunoGenesis |
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Employment - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Research Funding - ImmunoGenesis |
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No Relationships to Disclose |
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Employment - ImmunoGenesis |
Stock and Other Ownership Interests - ImmunoGenesis |
Research Funding - ImmunaGenesis |
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Leadership - ImmunoGenesis |
Stock and Other Ownership Interests - Agenus (I); Elicio Therapeutics (I); ImmunoGenesis; Relay Therapeutics (I) |
Consulting or Advisory Role - Agenus; Alligator Bioscience; AstraZeneca/MedImmune; Everest Medicine; ImmunOs Therapeutics; OncoResponse; Xencor |
Research Funding - ImmunoGenesis |
Patents, Royalties, Other Intellectual Property - The Regents of the University of California, James Allison and Michael Curran. Methods and Composition for Localized Secretion of Anti-CTLA-4 Antibodies, United States, US 9,868,961 B2.; The University of Texas MD Anderson Cancer Center, Philip Jones, Maria Emilia DiFrancesco, Michael A. Curran. Cyclic Dinucleotides as Agonists of Stimulator of Interferon Gene Dependent Signaling, United States, 62/461,642.; The University of Texas, MD Anderson Cancer Center, Michael A. Curran, Carlo Toniatti, Ashvin R. Jaiswal, Dongxing Zha, and Voo Kui. Dual specificity antibodies which bind both PD-L1 and PD-L2 and prevent their binding to PD-1, United States, PCT/US2019/0 |
Travel, Accommodations, Expenses - AstraZeneca/MedImmune |