The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Preliminary results from the randomized phase 2 study (1801 part 3B) of elraglusib in combination with gemcitabine/nab-paclitaxel (GnP) versus GnP alone in patients (pts) with previously untreated metastatic pancreatic ductal adenocarcinoma (mPDAC).
 
Devalingam Mahalingam
Consulting or Advisory Role - Actuate Therapeutics; Amgen; Qurient
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Eisai; Exelixis; Genentech
Research Funding - Amgen; Merck KGaA; Oncolytics
 
Rachna Shroff
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Genentech; Jazz Pharmaceuticals; Merck; Merus
Research Funding - Actuate Therapeutics; Bristol-Myers Squibb; Compass Therapeutics; Exelixis; Faeth Therapeutics; Fujifilm; Immunovaccine; Lisata; Loxo/Lilly; Merck; NGM Biopharmaceuticals; Novocure; Nucana; Rafael Pharmaceuticals; Seagen
 
Benedito Carneiro
Consulting or Advisory Role - ADC Therapeutics; Eisai; Seagen
Research Funding - Abbvie (Inst); Actuate Therapeutics (Inst); Agenus (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Bristol Myers Squibb (Inst); Dragonfly Therapeutics (Inst); MiNK Therapeutics (Inst); Pfizer (Inst); Pyxis (Inst); Regeneron (Inst); Repare Therapeutics (Inst)
 
Yan Ji
Consulting or Advisory Role - AstraZeneca; BeiGene; Janssen
 
Andrew Coveler
Consulting or Advisory Role - Actuate Therapeutics; Taiho Oncology
Research Funding - AbGenomics International (Inst); Actuate Therapeutics (Inst); Amgen (Inst); AstraZeneca (Inst); Mirati Therapeutics; Nextrast (Inst); Novocure (Inst); Nucana (Inst); Seagen (Inst); Surface Oncology (Inst)
Travel, Accommodations, Expenses - Abbvie; Halozyme; Nucana
 
Andres Cervantes
Consulting or Advisory Role - Abbvie; Foundation Medicine (Inst); Merck Serono (Inst); Roche (Inst)
Research Funding - Actuate Therapeutics (Inst); Adaptimmune (Inst); Amcure (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca Spain (Inst); Bayer (Inst); BeiGene (Inst); BMSi (Inst); FibroGen (Inst); Genentech (Inst); Lilly (Inst); MedImmune (Inst); Merck Serono (Inst); MSD (Inst); Natera (Inst); Novartis (Inst); SERVIER (Inst); Sierra Oncology (Inst); Takeda (Inst)
Other Relationship - Annals of Oncology; Cancer Treatment Reviews; ESMO Open
 
Vaibhav Sahai
Consulting or Advisory Role - AstraZeneca; Autem Medical; Delcath Systems; Elevar Therapeutics; Histosonics; Incyte; Ipsen; Jazz Pharmaceuticals; Lynx Group; Rafael Pharmaceuticals; SERVIER; Taiho Oncology
Research Funding - Actuate Therapeutics (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Elicio Therapeutics (Inst); Esanik (Inst); Exelixis (Inst); FibroGen (Inst); Ipsen (Inst); MedImmune (Inst); Pancreatic Cancer Action Network (Inst); Rafael Pharmaceuticals (Inst); Relay Therapeutics (Inst); Relay Therapeutics (Inst); Repare Therapeutics (Inst); SERVIER (Inst); Syros Pharmaceuticals (Inst); TransThera Biosciences (Inst)
Travel, Accommodations, Expenses - ASCO; Lynx Group
Other Relationship - Rafael Pharmaceuticals (Inst)
 
Anne Ploquin
No Relationships to Disclose
 
Sandrine Hiret
Consulting or Advisory Role - AstraZeneca; BMS; Roche; Sanofi; Takeda
Travel, Accommodations, Expenses - Novartis; Roche; Sanofi
 
Noelle LoConte
Consulting or Advisory Role - Abbvie; Abbvie; Personal Genome Diagnostics
Research Funding - Exact Sciences
 
Ivor Percent
No Relationships to Disclose
 
Charles Lopez
Consulting or Advisory Role - Ipsen
Research Funding - Roche/Genentech (Inst); Servier (Inst); Taiho Pharmaceutical (Inst)
 
Simon Pernot
No Relationships to Disclose
 
Petr Kavan
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Eisai; Merck; Novartis; Pfizer; Roche Canada; Taiho Pharmaceutical
 
Mary Mulcahy
No Relationships to Disclose
 
Ryan Carr
No Relationships to Disclose
 
Francis Giles
Stock and Other Ownership Interests - Actuate Therapeutics
Consulting or Advisory Role - MorphoSys
 
Andrew Mazar
Employment - Actuate Therapeutics
Leadership - Monopar Therapeutics
Stock and Other Ownership Interests - Actuate Therapeutics; Monopar Therapeutics
Patents, Royalties, Other Intellectual Property - UPAR patents Monopar, GSK-3 patents Actuate
 
Gil Fine
Honoraria - Actuate Therapeutics
Consulting or Advisory Role - Actuate Therapeutics
 
Tanios Bekaii-Saab
Consulting or Advisory Role - Abbvie; Amgen (Inst); Arcus Biosciences (Inst); AstraZeneca; Bayer (Inst); BeiGene; Boehringer Ingelheim; Caladrius Biosciences; Caladrius Biosciences; Celularity; Daiichi Sankyo/UCB Japan; Deciphera; Eisai; Eisai; Exact Sciences; Foundation Medicine; Foundation Medicine; Illumina; Immuneering; Incyte (Inst); Ipsen (Inst); Janssen; Kanaph Therapeutics; Lilly (Inst); Natera; Pfizer (Inst); Roche/Genentech (Inst); Seagen (Inst); SOBI; Stemline Therapeutics; Treos Bio; Zai Lab
Patents, Royalties, Other Intellectual Property - Patent WO/2018/183488; Patent WO/2019/055687
Other Relationship - 1Globe Health Institute; AstraZeneca; Exelixis; FibroGen; Imugene; Lilly; Merck (Inst); Pancreatic Cancer Action Network; Replimune; Sun Biopharma; Suzhou Kintor Pharmaceuticals; UpToDate; Xilis