The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Dauntless-1, a phase 2 clinical trial to evaluate PMD-026, a first-in-class pan-RSK inhibitor, combined with fulvestrant to overcome resistance to CDK4/6 inhibitors in advanced or metastatic HR+/HER2- breast cancer.
 
Sandra Dunn
Employment - Phoenix Molecular Designs
Leadership - Phoenix Molecular Designs
Stock and Other Ownership Interests - Phoenix Molecular Designs
Patents, Royalties, Other Intellectual Property - I am a co-inventor on multiple patents which relate to Phoenix Molecular Designs, the company I founded.
 
Hung Khong
Stock and Other Ownership Interests - agenus; MiNK Therapeutics; TG Therapeutics; Tiziana Life Sciences
Consulting or Advisory Role - Celcuity; Lilly
 
Muralidhar Beeram
Honoraria - Genentech (Inst); Johnson & Johnson (Inst)
Consulting or Advisory Role - Bayer (I); Merck (I); Novartis (I); Seagen (I)
Speakers' Bureau - Bristol-Myers Squibb (Inst); Genentech (Inst); Merck (Inst)
Research Funding - Agios (Inst); AstraZeneca (Inst); Lilly (Inst); Merck (Inst); Merrimack (Inst); Mersana (Inst); Pfizer (Inst); Phoenix Molecular Designs (Inst); Phoenix Molecular Designs (Inst); Puma Biotechnology (Inst); Zymeworks (Inst)
Travel, Accommodations, Expenses - Genentech; Merck
 
Robert Wesolowski
Consulting or Advisory Role - Celcuity; Celcuity; Pfizer
Other Relationship - Merck
 
Hyo Han
Consulting or Advisory Role - Arvinas; Pfizer
Research Funding - Arvinas (Inst); Celcuity (Inst); Department of Defense (Inst); Eisai; Ellipses Pharma; Mersana; Pfizer (Inst); Phoenix Pharmaceuticals (Inst); Pionyr (Inst); QuantumLeap Health (Inst); Senhwa Biosciences (Inst); Zymeworks (Inst)
 
Nicolaos Palaskas
Employment - UCLA
Stock and Other Ownership Interests - Athos Therapeutics; Torl Biotherapeutics
Research Funding - Merck (Inst); Orum Therapeutics (Inst); Phoenix Molecular Designs (Inst); Protagonist Therapeutics (Inst); RayzeBio (Inst)
 
Aarthi Jayanthan
Employment - Phoenix Molecular Designs
Leadership - Phoenix Molecular Designs (Inst)
Stock and Other Ownership Interests - Phoenix Molecular Designs (Inst)
Research Funding - Phoenix Molecular Designs (Inst)
Patents, Royalties, Other Intellectual Property - Phoenix Molecular Designs (Inst)
 
Martin Olivo
Employment - Protara Therapeutics; Systimmune
Leadership - Protara Therapeutics; Systimmune
Stock and Other Ownership Interests - Gilead Sciences; Protara Therapeutics; SystImmune
(OPTIONAL) Uncompensated Relationships - Phoenix Molecular Designs
 
Brian Barnett
Employment - Phoenix Molecular Designs
Stock and Other Ownership Interests - Phoenix Molecular Designs