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EVEREST-1: Safety and efficacy data of A2B530, a logic-gated Tmod chimeric antigen receptor T-cell (CAR T) therapy, in patients with solid tumors associated with carcinoembryonic antigen (CEA) expression and with human leukocyte antigen (HLA) loss of heterozygosity (LOH). |
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No Relationships to Disclose |
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Employment - Walgreens (I) |
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Consulting or Advisory Role - AstraZeneca |
Patents, Royalties, Other Intellectual Property - Compositions and Methods for the Treatment of Pancreatic Cancer |
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Stock and Other Ownership Interests - Actym Therapeutics; Rafael Pharmaceuticals; Trumvira |
Consulting or Advisory Role - Agenus; Astellas Pharma; BeiGene; Bristol-Myers Squibb/Medarex; Galvanize Therapeutics; MBQ Pharma; Revolution Medicines; Taiho Pharmaceutical; Xilio Therapeutics |
Research Funding - A2 Biotherapeutics (Inst); Affini-T Therapeutics (Inst); Agenus (Inst); Amgen (Inst); Bold Therapeutics (Inst); Camurus (Inst); Cardiff Oncology (Inst); CG Pharmaceuticals (Inst); Crinetics Pharmaceuticals (Inst); Exelixis (Inst); Gilead Sciences (Inst); Gritstone Bio (Inst); Janssen Oncology (Inst); Lyell Immunopharma (Inst); Merck (Inst); Mirati Therapeutics (Inst); Neogene Therapeutics (Inst); NGM Biopharmaceuticals (Inst); Regeneron (Inst); Revolution Medicines (Inst); Seagen (Inst); Tizona Therapeutics, Inc. (Inst); Tizona Therapeutics, Inc. (Inst); Xilio Therapeutics (Inst) |
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Consulting or Advisory Role - Amgen; AstraZeneca/MedImmune; BeiGene; Bristol-Myers Squibb; Certis Oncology Solutions; Compugen; Illumina; Iovance Biotherapeutics (Inst); Lilly; Lilly; Merck; Nektar; Novartis; Pfizer; Roche/Genentech; Tempus |
Speakers' Bureau - Boehringer Ingelheim; Merck |
Research Funding - Amgen (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Fate Therapeutics (Inst); Iovance Biotherapeutics (Inst); Merck (Inst); Pfizer (Inst); Roche/Genentech (Inst); Rubius Therapeutics; Takeda (Inst); Takeda (Inst) |
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Leadership - Immodulon; Immunovia |
Stock and Other Ownership Interests - Longevity Life Advisors |
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Consulting or Advisory Role - FibroGen |
Research Funding - Biological Dynamics; Clearnote Health; Immunovia; Micronoma |
Patents, Royalties, Other Intellectual Property - small royalties for my patent on pancreatic cancer stem cells also I receive an annual royalty for a textbook I edited Greenfields Textbook of Surgery |
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No Relationships to Disclose |
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Leadership - MyCareGorithm |
Stock and Other Ownership Interests - Agenus; Oncternal Therapeutics; Veru |
Consulting or Advisory Role - MyCareGorithm |
Research Funding - Turnstone Bio |
Travel, Accommodations, Expenses - A2Bio |
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No Relationships to Disclose |
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Consulting or Advisory Role - AstraZeneca; Bayer; Boston Scientific; BPG Bio; Bristol-Myers Squibb; Genomic Health; STERIS |
Research Funding - Bayer (Inst); Celgene; Chronix Biomedical (Inst) |
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Stock and Other Ownership Interests - A2 Biotherapeutics |
Honoraria - A2 Biotherapeutics; Bristol-Myers Squibb/Celgene; Genentech/Roche; Gilead Sciences; Kite, a Gilead company; Lyell Immunopharma; Novartis; Umoja Biopharma |
Consulting or Advisory Role - A2 Biotherapeutics; Celgene/Bristol-Myers Squibb; Genentech; NAVAN Technologies |
Research Funding - Celgene (Inst); Juno Therapeutics (Inst); Kite, a Gilead company (Inst) |
Patents, Royalties, Other Intellectual Property - Inventor on 4 provisional patents. |
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Consulting or Advisory Role - A2 Biotherapeutics; Alimera Sciences; Amgen; Bluebird Bio; Bristol-Myers Squibb; Bristol-Myers Squibb/Celgene; Calibr; Caribou Biosciences; Celgene; Cowen; Daiichi Sankyo/UCB Japan; EcoR1 Capital; Gerson Lehrman Group; Iovance Biotherapeutics; Janssen; Kite, a Gilead company; Legend Biotech; Miltenyi Biotec; Novartis; Sana Biotechnology; Takeda; Takeda; Umoja Biopharma |
Research Funding - Alimera Sciences (Inst); Bluebird Bio (Inst); Bristol-Myers Squibb/Celgene (Inst); Kite, a Gilead company (Inst); Novartis (Inst) |
Patents, Royalties, Other Intellectual Property - CAR T Cells with Enhanced Metabolic Fitness. Serial Number: 62/939,727 (Inst); Double Mutant Survivin Vaccine. US010414810B2. (Inst); Evolutionary Dynamics of Non-Hodgkin Lymphoma CAR-T cell therapy. Serial Number: 62/879,534. (Inst); Methods of Enhancing CAR T Cell Therapies. Serial Number: 62/892,292. (Inst) |
Travel, Accommodations, Expenses - A2 Biotherapeutics; Kite, a Gilead company |
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Leadership - 2seventy bio |
Stock and Other Ownership Interests - 2seventy bio; A2Bio; Affyimumune; BendBio; CARGO Therapeutics; GBM newco; Model T Bio; NexImmune; Oncternal Therapeutics |
Consulting or Advisory Role - Adaptimmune; AffyImmune Therapeutics; Agenus; arcellx; Astellas Pharma; AstraZeneca; Atara Biotherapeutics; Bayer; BMS; Cabaletta Bio; Cabaletta Bio; Chugai Pharma; crispr therapeutics; GlaxoSmithKline; In8Bio; In8bio; Intellia Therapeutics; Kite, a Gilead company; MicroMedicine; Novartis; Oncternal Therapeutics; Sanofi; TCR2 Therapeutics; Tmunity Therapeutics, Inc.; Torque; windmil |
Research Funding - Kite, a Gilead company (Inst); Moderna Therapeutics (Inst); Servier (Inst); Sobi (Inst) |
Patents, Royalties, Other Intellectual Property - Inventor on patents held by Massachusetts General Hospital/Partners Health care; all related to CAR T cells and/or gene therapy; Inventor on patents held by U. Pennsylvania with and without Novartis |
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Stock and Other Ownership Interests - A2 Biotherapeutics; Adaptive Biotechnologies; Adicet Bio |
Honoraria - Poseida Therapeutics |
Consulting or Advisory Role - A2 Biotherapeutics; Lyell Immunopharma |
Speakers' Bureau - Bristol-Myers Squibb; Kite, a Gilead Company |
Research Funding - Crispr Therapeutics |
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Employment - A2 Biotherapeutics |
Stock and Other Ownership Interests - A2 Biotherapeutics |
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Employment - A2 Biotherapeutics |
Stock and Other Ownership Interests - A2 Biotherapeutics |
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Employment - A2 Biotherapeutics |
Stock and Other Ownership Interests - A2 Biotherapeutics |
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Employment - A2 Biotherapeutics |
Stock and Other Ownership Interests - A2 Biotherapeutics |
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No Relationships to Disclose |
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Consulting or Advisory Role - ADC Therapeutics; Autolus; Bristol-Myers Squibb/Celgene/Juno; Genentech; Kura Oncology; Stemline Therapeutics |
Research Funding - Immunogen; Kite, a Gilead company |
Travel, Accommodations, Expenses - Miltenyi Biotec |
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Research Funding - A2 Biotherapeutics (Inst); Affini-T Therapeutics (Inst); Amgen (Inst); Astellas Pharma (Inst); Constellation Pharmaceuticals (Inst); NCI (Inst); Neogene Therapeutics (Inst); Prelude Therapeutics (Inst); Revolution Medicines (Inst); Simcere (Inst); Tango Therapeutics (Inst); VITRAC Therapeutics (Inst) |