The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase 1, first-in-human study of ISB 2001: A BCMAxCD38xCD3-targeting trispecific antibody for patients with relapsed/refractory multiple myeloma (RRMM)—Dose escalation (DE) results.
 
Eben Lichtman
Consulting or Advisory Role - Abbvie; Lilly (I); Novartis (I); UCB (I)
Research Funding - Abbvie (Inst); Bristol Myers Squibb Foundation (Inst); GlaxoSmithKline (Inst); Pfizer (I); Poseida (Inst); Sanofi (Inst); sonoma pharmaceuticals (I)
 
Amit Khot
Consulting or Advisory Role - CURE Therapeutics; GlaxoSmithKline; Janssen
 
Bradley Augustson
No Relationships to Disclose
 
David Levitz
No Relationships to Disclose
 
Hanlon Sia
No Relationships to Disclose
 
Nicole Wong Doo
No Relationships to Disclose
 
Michaela Liedtke
Consulting or Advisory Role - Abbvie; Alexion Pharmaceuticals; Arcellx; AstraZeneca; Jazz Pharmaceuticals; Prothena; Sanofi
 
Camille Martinet
No Relationships to Disclose
 
Vinu Menon
No Relationships to Disclose
 
Andrew Garton
Employment - IGI Inc.
 
Harjeet Sembhi
Employment - GlaxoSmithKline; IGI Inc.
 
Maria Pihlgren
Employment - IGI Biotherapeutics
Stock and Other Ownership Interests - AC Immune
Patents, Royalties, Other Intellectual Property - Patent for ISB 2001
Travel, Accommodations, Expenses - IGI Biotherapeutics
 
Cyril Konto
Employment - IGI
Leadership - IGI
Stock and Other Ownership Interests - Bristol-Myers Squibb; IGI; Pfizer
Patents, Royalties, Other Intellectual Property - CART patent: US20200261503A1; US20240041930A1; AR117170A1; AR113814A1; NZ805037A
 
Beata Holkova
Employment - IGI Inc., NY; Janssen Oncology
Stock and Other Ownership Interests - Janssen Oncology
Research Funding - IGI Inc., NY; Janssen Oncology
Travel, Accommodations, Expenses - IGI Inc., NY; Janssen Oncology
 
Lida Pacaud
Employment - IGI Ichnos Glenmark Innovation
Leadership - IGI Ichnos Glenmakr Innovation
Stock and Other Ownership Interests - IGI Ichnos Glenmakr Innovation; Legend Biotech
 
Hang Quach
Consulting or Advisory Role - Antengene (Inst); Bristol-Myers Squibb/Celgene; GlaxoSmithKline (Inst); Janssen-Cilag; Karyopharm Therapeutics (Inst); Pfizer; Roche; Sanofi (Inst)
Research Funding - Amgen; Bristol-Myers Squibb/Celgene; Celgene; GlaxoSmithKline; Karyopharm Therapeutics; Sanofi