The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Serum estradiol (sE2) levels in premenopausal (PreM) women receiving neoadjuvant ovarian function suppression (OFS) with the oral SERD amcenestrant, alone, or in combination with letrozole or abemaciclib in the I-SPY2 Endocrine Optimization Pilot (EOP).
 
Jo Chien
Consulting or Advisory Role - Genentech/Roche
Research Funding - Amgen (Inst); Merck (Inst); Olema Oncology (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Seagen (Inst)
Patents, Royalties, Other Intellectual Property - Pending Patent Application for “COMBINATION INCLUDING A CPG-C TYPE OLIGONUCLEOTIDE AND A PD-1 ANTAGONIST FOR TREATING BREAST CANCER”
Travel, Accommodations, Expenses - Genentech/Roche
 
Peter Norwood
Employment - Parexel (I); Quantum Leap Healthcare Collaborative
Research Funding - Quantum Leap Healthcare Collaborative
Travel, Accommodations, Expenses - Quantum Leap Healthcare Collaborative
 
Rita Mukhtar
Research Funding - GE Healthcare
Patents, Royalties, Other Intellectual Property - Patent on the use of fibrin and silver microparticles to promote wound healing. (I)
 
Karthik Giridhar
Consulting or Advisory Role - AstraZeneca/Daiichi Sankyo (Inst); Exact Sciences (Inst); Gilead Sciences (Inst); Lilly (Inst); MJH Live Events (Inst); MJH Live Events (Inst); NeoGenomics Laboratories (Inst); Puma Biotechnology (Inst); Tersera (Inst)
Research Funding - Guardant Health (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - GRAIL; QuantumLeap Health
 
Matthew Goetz
Consulting or Advisory Role - ARC Therapeutics (Inst); ARC Therapeutics (Inst); AstraZeneca (Inst); AstraZeneca (Inst); Atossa Therapeutics (Inst); BeiGene (Inst); bioTheranostics (Inst); BioTheryX; Biovica (Inst); Blueprint Medicines (Inst); Context Therapeutics (Inst); Eagle Pharmaceuticals (Inst); eChinaHealth (Inst); EcoR1 Capital (Inst); Engage Health Media (Inst); Genentech (Inst); Genomic Health (Inst); Genzyme (Inst); Genzyme (Inst); Incyclix Bio (Inst); Intellisphere (Inst); Laekna Therapeutics; Lilly (Inst); Loxo (Inst); Novartis (Inst); Puma Biotechnology (Inst); Rna Diagnostics (Inst); Seagen (Inst); Seagen (Inst); Sermonix Pharmaceuticals (Inst); Sermonix Pharmaceuticals (Inst); Tersera
Research Funding - AstraZeneca (Inst); Atossa Genetics (Inst); BioTheryX (Inst); Lilly (Inst); Loxo (Inst); Pfizer (Inst); Sermonix Pharmaceuticals (Inst); SimBioSys (Inst)
Travel, Accommodations, Expenses - Lilly (Inst)
(OPTIONAL) Uncompensated Relationships - Symbios
 
Christos Vaklavas
Employment - Flatiron Health (I)
Honoraria - AstraZeneca; Cardinal Health; Cardinal Health; Daiichi Sankyo/Astra Zeneca; Daiichi Sankyo/Astra Zeneca; Gilead Sciences; Guidepoint Global; Novartis; Pfizer; Pfizer; Seagen
Consulting or Advisory Role - AstraZeneca; AstraZeneca; Daiichi Sankyo; Genentech; Gilead Sciences
Research Funding - AstraZeneca (Inst); AstraZeneca/Daiichi Sankyo (Inst); Daiichi Sankyo/UCB Japan (Inst); Genentech (Inst); H3 Biomedicine (Inst); Incyte (Inst); Innocrin Pharma (Inst); Novartis (Inst); Pfizer (Inst); Pharmacyclics (Inst); Roche (Inst); Seagen (Inst); TRACON Pharma (Inst); Zymeworks (Inst)
Other Relationship - Daiichi Sankyo; Puma Biotechnology; Takeda
(OPTIONAL) Uncompensated Relationships - Genentech
 
Anthony Elias
Stock and Other Ownership Interests - Abbott Laboratories; Abbvie; Alexion Pharmaceuticals; Align Oncology; Allergan; Amgen; Bristol-Myers Squibb; Cigna; Exact Sciences; Gilead Sciences; Illumina; Lilly; Merck; Pfizer
Consulting or Advisory Role - Arvinas; Caris Life Sciences; Ellipses Pharma
Research Funding - ImmuneOnco Biopharmaceuticals (Inst); Scorpion Therapeutics (Inst)
 
Mei Wei
Consulting or Advisory Role - Arvinas; AstraZeneca; bioTheranostics; Gilead Sciences; Merck; Novartis; Relay Therapeutics
Patents, Royalties, Other Intellectual Property - From Ambry Genetics for a software (I)
 
Hope Rugo
Honoraria - Chugai Pharma; Mylan/Viatris
Consulting or Advisory Role - Bristol Meyer; Napo Pharmaceuticals; Sanofi
Research Funding - Ambryx (Inst); AstraZeneca (Inst); Daiichi Sankyo (Inst); Gilead Sciences (Inst); Hoffmann-La Roche AG/Genentech, Inc (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Pfizer (Inst); Stemline Therapeutics (Inst)
 
Nan Chen
Employment - GlaxoSmithKline (I)
Consulting or Advisory Role - AstraZeneca; GE Healthcare; Gilead Sciences; Guardant Health; Seagen; Stemline Therapeutics
 
Alexander Borowsky
Leadership - Histolix
Stock and Other Ownership Interests - Histolix
Consulting or Advisory Role - Tempus
Research Funding - Danaher (Inst)
 
Lamorna Brown Swigart
No Relationships to Disclose
 
Rebecca Shatsky
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/Astra Zeneca; Endeavor BioMedicines; Guardant Health; Lilly; Novartis; Stemline Therapeutics; TEMPUS
Research Funding - AstraZeneca (Inst); Briacell (Inst); Gilead Sciences (Inst); Greenwich LifeSciences (Inst); OBI Pharma (Inst); OnKure (Inst); QuantumLeap Health (Inst); Regor Therapeutics (Inst); Stemline Therapeutics (Inst)
 
Laura Huppert
Consulting or Advisory Role - AstraZeneca; Pfizer
Research Funding - Greenwich LifeSciences (Inst)
Patents, Royalties, Other Intellectual Property - Book royalties: McGraw Hill
 
Michelle Melisko
Stock and Other Ownership Interests - Merrimack (I)
Consulting or Advisory Role - Genentech
Speakers' Bureau - AstraZeneca (I); Daiichi Sankyo/Astra Zeneca (I); Gilead Sciences (I)
Research Funding - DAEHWA Pharmaceutical (Inst); OBI Pharma (Inst); Puma Biotechnology (Inst)
Patents, Royalties, Other Intellectual Property - Multiple patents related to immunoliposomal drugs being studied and potentially brought to market by Merrimack (I)
Expert Testimony - GlaxoSmithKline
 
Laura Esserman
Consulting or Advisory Role - Blue Cross Blue Shield Association
Research Funding - Moderna Therapeutics (Inst)
Travel, Accommodations, Expenses - Blue Cross Blue Shield Association
(OPTIONAL) Uncompensated Relationships - Quantum Leap Healthcare Collaborative