The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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INAVO120: Phase III trial final overall survival (OS) analysis of first-line inavolisib (INAVO)/placebo (PBO) + palbociclib (PALBO) + fulvestrant (FULV) in patients (pts) with PIK3CA-mutated, hormone receptor-positive (HR+), HER2-negative (HER2–), endocrine-resistant advanced breast cancer (aBC).
 
Nicholas Turner
Consulting or Advisory Role - AstraZeneca; Exact Sciences; Gilead Sciences; GlaxoSmithKline; Guardant Health; Inivata; Lilly; Merck Sharp & Dohme; Novartis; Pfizer; Relay Therapeutics; Repare Therapeutics; Roche
Research Funding - AstraZeneca (Inst); Guardant Health (Inst); Inivata (Inst); InVitae (Inst); Merck Sharpe and Dohme (Inst); Natera (Inst); Personalis (Inst); Pfizer (Inst); Roche (Inst)
 
Seock-Ah Im
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo; Eisai; Lilly; MSD; Novartis; Pfizer; Roche/Genentech
Research Funding - AstraZeneca (Inst); Boryung Pharmaceuticals (Inst); Daiichi Sankyo (Inst); Eisai (Inst); Pfizer (Inst); Roche/Genentech (Inst)
Other Relationship - Roche
(OPTIONAL) Uncompensated Relationships - Roche
 
Cristina Saura
Consulting or Advisory Role - AstraZeneca, AX'S Consulting sprl, Byondis B.V., Daiichi Sankyo, Eisai, Exact, Exeter Pharma, Fondazione Internazionale Menarini, Gilead Sciences (aka Gilead Foundation), Lilly, MediTech, MSD, Novartis, PFIZER, Philips, Pierre Fabre, PintPharma, Puma Biot
(OPTIONAL) Uncompensated Relationships - Research funding in the form of third-party medical writing support, furnished by Eleanor Porteus, MSc, of Nucleus Global, an Inizio Company, was provided by F. Hoffmann-La Roche Ltd (Basel, Switzerland).
 
Dejan Juric
Consulting or Advisory Role - AstraZeneca, Eisai, Inc., Eli Lilly and Company, F. Hoffmann-La Roche Ltd, Genentech, Inc., Mapkure, Novartis, Pfizer, Relay Therapeutics, Syros Pharmaceuticals, Vibliome
Research Funding - Amgen, Inc., AstraZeneca, Blueprint Medicines, Eisai, Eli Lilly, F. Hoffmann-La Roche Ltd, Genentech, Inc., Infinity Pharmaceuticals, Novartis, Pfizer, Ribon Therapeutics, Scorpion Therapeutics, Seagen, Syros, Takeda (Inst)
(OPTIONAL) Uncompensated Relationships - Research funding in the form of third-party medical writing support, furnished by Eleanor Porteus, MSc, of Nucleus Global, an Inizio Company, was provided by F. Hoffmann-La Roche Ltd (Basel, Switzerland)
 
Sibylle Loibl
Employment - Bethanien Krankenhaus
Consulting or Advisory Role - Abbvie (Inst); Amgen (Inst); AstraZeneca/MedImmune (Inst); BeiGene (Inst); Bicycle Therapeutics (Inst); BMS (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo (Inst); Eisai Europe (Inst); GlaxoSmithKline (Inst); Jazz Pharmaceuticals (Inst); Lilly (Inst); Menarini Group (Inst); MSD Oncology (Inst); Novartis (Inst); Olema Pharmaceuticals (Inst); Pfizer (Inst); Relay Therapeutics (Inst); Roche (Inst); Sanofi (Inst); Seagen (Inst)
Speakers' Bureau - Agendia (Inst); AstraZeneca (Inst); Bayer (Inst); Daiichi Sankyo Europe GmbH (Inst); Gilead Sciences (Inst); Medscape (Inst); Menarini Group (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst); Seagen (Inst); Stemline Therapeutics (Inst); Streamedup! (Inst)
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Gilead Sciences (Inst); Greenwich LifeSciences (Inst); Menarini Group (Inst); MolecularHealth (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst)
Patents, Royalties, Other Intellectual Property - Digital Ki67 Evaluator, VM Scope GmbH (Inst); Patent Issued EP15702464.7 (Inst); Patent Pending EP14153692.0 (Inst); Patent Pending EP19808852.8 (Inst); Patent Pending EP21152186.9 (Inst)
Travel, Accommodations, Expenses - AstraZeneca (Inst); MSD (Inst); Roche (Inst)
 
Kevin Kalinsky
Employment - EQRx (I)
Stock and Other Ownership Interests - EQRx (I)
Consulting or Advisory Role - AstraZeneca; bioTheranostics; Cullinan Oncology; Daiichi Sankyo/Astra Zeneca; eFFECTOR Therapeutics; Genentech/Roche; Gilead Sciences; Lilly; Menarini Silicon Biosystems; Merck; mersana; Mersana; Myovant Sciences; Novartis; Pfizer; Prelude Therapeutics; ProteinQure; Puma Biotechnology; RayzeBio; Regor; Relay Therapeutics; Takeda
Research Funding - Ascentage Pharma (Inst); AstraZeneca (Inst); Daichi Sankyo (Inst); Genentech/Roche (Inst); Lilly (Inst); Novartis (Inst); Seagen (Inst)
 
Peter Schmid
Employment - Roche (I)
Honoraria - AstraZeneca; Bayer; Bayer; Boehringer Ingelheim; Celgene; Celgene; Eisai; Genentech (Inst); Gilead Sciences Hong Kong; Merck; Novartis; Oncogenex (Inst); Oncogenex (Inst); Pfizer; Puma Biotechnology; Roche; Sanofi; Stemline Therapeutics
Consulting or Advisory Role - AstraZeneca; Bayer; Boehringer Ingelheim; Celgene; Eisai; Genentech/Roche (I); Merck; Novartis; Pfizer; Puma Biotechnology
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Genentech (Inst); Medivation; Novartis (Inst); Oncogenex (Inst); Roche (Inst)
Travel, Accommodations, Expenses - ESMO; SABS
 
Sherene Loi
Honoraria - Adanate; Amaroq Therapeutics; Astra Zeneca / Daiichi Sankyo; Bicycle Therapeutics; BioNTech SE; Domain Therapeutics; Exact Sciences; Gilead Sciences; Menari Asia Pacific; Mersana; MSD Oncology; Novartis; Roche/Genentech; SAGA Diagnostics
Consulting or Advisory Role - AstraZeneca (Inst); BMS (Inst); Gilead Sciences (Inst); Lilly (Inst); MSD Oncology (Inst); Nektar (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst)
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Gilead Sciences (Inst); Lilly (Inst); MSD Oncology (Inst); Nektar (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - BMS
Other Relationship - Roche Medical writing support
 
Eirini Thanopoulou
Employment - Roche
Stock and Other Ownership Interests - Roche
Patents, Royalties, Other Intellectual Property - Roche
(OPTIONAL) Uncompensated Relationships - Research funding in the form of third-party medical writing support, furnished by Eleanor Porteus, MSc, of Nucleus Global, an Inizio Company, was provided by F. Hoffmann-La Roche Ltd (Basel, Switzerland)
 
Noopur Shankar
Employment - Genentech
Stock and Other Ownership Interests - Roche/Genentech
Travel, Accommodations, Expenses - Genentech/Roche
 
Yanling Jin
Employment - Roche/Genentech
Stock and Other Ownership Interests - Roche/Genentech
 
Thomas Stout
Employment - Genentech/Roche
Stock and Other Ownership Interests - Roche/Genentech
 
Tiffany D Clark
Employment - Genentech/Roche; Gilead Sciences (I)
Stock and Other Ownership Interests - Genentech/Roche (Inst); Gilead Sciences (I)
Research Funding - Genentech/Roche (Inst); Gilead Sciences (I)
Patents, Royalties, Other Intellectual Property - Assorted patents owned by Gilead are credited to my husband (I)
Travel, Accommodations, Expenses - Genentech/Roche (Inst); Gilead Sciences (I)
 
Chunyan Song
Employment - Genentech
Stock and Other Ownership Interests - Roche
(OPTIONAL) Uncompensated Relationships - Research funding in the form of third-party medical writing support, furnished by Eleanor Porteus, MSc, of Nucleus Global, an Inizio Company, was provided by F. Hoffmann-La Roche Ltd (Basel, Switzerland)
 
Komal Jhaveri
Consulting or Advisory Role - Abbvie; AstraZeneca; Bicycle Therapeutics; Biotheranostics; BluePrint Medicines; Bristol-Myers Squibb; Daiichi Sankyo; Eisai; Genentech; Gilead Sciences; Lilly; Novartis; Pfizer; Sanofi; Scorpion Therapeutics; Seagen
Research Funding - AstraZeneca (Inst); Blueprint Medicines (Inst); Context Therapeutics (Inst); Genentech (Inst); Gilead Sciences (Inst); Lilly (Inst); Novartis (Inst); Pfizer (Inst); Puma Biotechnology (Inst); RayzeBio (Inst); Scorpion Therapeutics (Inst); VelosBio/Merck (Inst); Zymeworks (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Genentech/Roche; Gilead Sciences; Intellisphere; Jounce Therapeutics; Lilly; Pfizer; Taiho Pharmaceutical