The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Efficacy and safety of selumetinib in adults with neurofibromatosis type 1 (NF1) and symptomatic, inoperable plexiform neurofibroma (PN): Primary analysis of KOMET (NCT04924608), a phase 3, international, randomized, placebo-controlled study.
 
Alice Chen
Research Funding - AstraZeneca (Inst); Genentech/Roche (Inst)
 
Geraldine O'Sullivan Coyne
Consulting or Advisory Role - GlaxoSmithKline
Travel, Accommodations, Expenses - Novartis Ireland Ltd.
 
Pamela Wolters
Stock and Other Ownership Interests - Bristol-Myers Squibb (under the amount allowable by the NIH)
 
Staci Martin
No Relationships to Disclose
 
Said Farschtschi
Honoraria - Alexion Pharmaceuticals
Consulting or Advisory Role - Alexion Pharmaceuticals
Research Funding - AstraZeneca
Travel, Accommodations, Expenses - Alexion Pharmaceuticals
 
Ignacio Blanco
Consulting or Advisory Role - Alexion Pharmaceuticals; SpringWorks Therapeutics
Travel, Accommodations, Expenses - Alexion Pharmaceuticals
 
Zhongping Chen
No Relationships to Disclose
 
Luiz Darrigo Junior
Consulting or Advisory Role - AstraZeneca
Speakers' Bureau - AstraZeneca
Research Funding - AstraZeneca
Travel, Accommodations, Expenses - AstraZeneca
 
Marica Eoli
Research Funding - Alexion Pharmaceuticals; Genenta Science
 
James Whittle
Leadership - Brain Cancer Centre; COGNO; Mark Hughes Foundation
Consulting or Advisory Role - Anheart Therapeutics; Servier/Pfizer
Research Funding - Anheart Therapeutics (Inst); Cancer Council Victoria (Inst); Carries Beanies for Brain Cancer (Inst); Flicker of Hope (Inst); MRFF (Inst); National Health and Medical Research Council (Inst); Perpetual (Inst); Victorian Cancer Agency (Inst)
Patents, Royalties, Other Intellectual Property - The Walter and Eliza Hall Institute receives milestone and royalty payments related to venetoclax (Inst)
 
Yoshihiro Nishida
Honoraria - Alexion Pharmaceuticals; Asahi Kasei; Astellas Pharma; Chugai Pharma; Daiichi Sankyo; Eisai; Hisamitsu Pharmaceutical; Kaken Pharmaceutical; Kyowa Hakko Kirin Co., Ltd.; Lilly Japan; Ono Pharmaceutical
Consulting or Advisory Role - Alexion Pharmaceuticals; Boehringer Ingelheim; Daiichi Sankyo; Seikagaku
Research Funding - Alexion Pharmaceuticals; Boehringer Ingelheim; daiichi Sankyo; Kuraray
 
Rosa Lamarca
Employment - Alexion, AstraZeneca Rare Disease
Leadership - Alexion, AstraZeneca Rare Disease
Stock and Other Ownership Interests - AstraZeneca
Honoraria - Alexion, AstraZeneca Rare Disease
Research Funding - Alexion, AstraZeneca Rare Disease
 
Randolph de la Rosa
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
Honoraria - AstraZeneca
Travel, Accommodations, Expenses - AstraZeneca
 
Ayo Adeyemi
Employment - Alexion, AstraZeneca Rare Disease
Stock and Other Ownership Interests - Alexion, AstraZeneca Rare Disease
 
Idoia Herrero
Employment - Alexion Pharmaceuticals
Stock and Other Ownership Interests - Alexion Pharmaceuticals
 
Nereida Llorente
Stock and Other Ownership Interests - Alexion Pharmaceuticals
 
Scott Diede
Employment - Merck Sharp & Dohme
Stock and Other Ownership Interests - Merck Sharp & Dohme
 
Eva Dombi
No Relationships to Disclose
 
Pierre Wolkenstein
Employment - Biocodex (I)
Honoraria - Alexion, AstraZeneca Rare Disease; SpringWorks Therapeutics
Consulting or Advisory Role - Alexion, AstraZeneca Rare Disease; SpringWorks Therapeutics
Travel, Accommodations, Expenses - Alexion, AstraZeneca Rare Disease