The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
Colorectal Cancer Metastatic dMMR Immunotherapy (COMMIT) study: A randomized phase III study of atezolizumab (atezo) monotherapy versus mFOLFOX6/bevacizumab/atezo (FFX/bev) in the first-line treatment of patients (pts) with deficient DNA mismatch repair (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC)— NRG-GI004/SWOG-S1610.
 
Caio Max Rocha Lima
Research Funding - Amgen; Amgen Astellas BioPharma
 
Greg Yothers
Employment - Mountainview Pediatrics (I)
Consulting or Advisory Role - Orbus Therapeutics
 
Thomas George
Consulting or Advisory Role - Arbele; Avammune Therapeutics; BillionToOne; Exact Sciences; Janssen Oncology; KAHR Medical; Nihon Medi-Physics; Summit Therapeutics
Research Funding - Amal Therapeutics (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); BillionToOne (Inst); BioMed Valley Discoveries (Inst); Bristol-Myers Squibb (Inst); Deciphera (Inst); Elicio Therapeutics (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Ipsen (Inst); Jounce Therapeutics (Inst); Lilly (Inst); Merck (Inst); OncoC4 (Inst); Regeneron (Inst); Seagen (Inst)
 
Howard Hochster
Stock and Other Ownership Interests - Compass Therapeutics
Consulting or Advisory Role - Processa Pharmaceuticals; Regeneron
Expert Testimony - Natera
Travel, Accommodations, Expenses - Takeda
Other Relationship - Seagen
 
Hanna Sanoff
Research Funding - Abbvie (Inst); Abbvie (Inst); Amgen (Inst); AstraZeneca (Inst); biogen (I); BioMed Valley Discoveries (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Johnson & Johnson/Janssen (Inst); Pfizer (Inst); Rgenix (Inst); Roche (Inst)
 
Deirdre Cohen
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Fosun Pharma; Summit Therapeutics
Speakers' Bureau - Guardant Health
Research Funding - Merck (Inst); Viome (Inst)
 
Katherine Guthrie
No Relationships to Disclose
 
Samuel Jacobs
Employment - Exact Sciences
Consulting or Advisory Role - Exact Sciences
 
Anwaar Saeed
Consulting or Advisory Role - Arcus therapeutics; Astellas Pharma; AstraZeneca; Autem therapeutics; Autem Therapeutics; BeOne therapeutics; Bristol-Myers Squibb; Exelixis; Pfizer; Regeneron; Replimune; Taiho Pharmaceutical; Xilio therapeutics
Research Funding - Actuate Therapeutics (Inst); Arcus therapeutics (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); BeOne therapeutics (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Incyte (Inst); KAHR Medical (Inst); Merck Sharp & Dohme (Inst); Oxford biotherapeutics (Inst); Phanes Therapeutics (Inst); Replimune (Inst)
 
Scott Kopetz
Stock and Other Ownership Interests - Frontier Medicines; Lutris; Navire
Consulting or Advisory Role - Alentis Therapeutics; AmMax Bio; Arcus Biosciences; AstraZeneca; AVEO; BeiGene; BioNTech SE; Boehringer Ingelheim; Bristol-Myers Squibb/Medarex; Carina Biotech; Clasp Therapeutics; Cytovation; Dewpoint Therapeutics; EMD Serono; Erasca, Inc; Flame Biosciences; Frontier Medicines; Genentech; Harbinger Oncology, Inc; Ikena Oncology; Iterion Therapeutics; Kivu Biosciences; Marengo Therapeutics; Pfizer; Regeneron; Roche; SageMedic; SERVIER; Shionogi; T-Cypher Bio; Tachyon Therapeutics; Transcode; XAIRA Therapeutics; Zentalis; Zentalis
Research Funding - Boehringer Ingelheim; EMD Serono; Genentech; Pfizer; Roche; Zentalis
 
Linda Colangelo
No Relationships to Disclose
 
Tanner Freeman
No Relationships to Disclose
 
Scott Cole
Honoraria - DAVA Oncology
Consulting or Advisory Role - Bayer; HERON; ONCare Alliance; Revolution Medicines; Seattle Genetics/Astellas
Travel, Accommodations, Expenses - Bayer; Bayer; HERON; Revolution Medicines
 
Dan Zuckerman
Leadership - OncoHealth Medical Group, PA
Consulting or Advisory Role - AstraZeneca; Oncology Analytics; Revolution Medicines
 
Theodore Hong
Stock and Other Ownership Interests - PanTher Therapeutics
Consulting or Advisory Role - Boston Scientific; Merck; nanobiotix; NextCure; Novocure; Synthetic Biologics; Zola
Research Funding - AstraZeneca (Inst); Bristol Myers Squibb (Inst); IntraOp (Inst); Ipsen (Inst); Taiho Pharmaceutical (Inst); Tesaro (Inst)
 
Norah Henry
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/Astra Zeneca; Genentech
Patents, Royalties, Other Intellectual Property - Royalty from Up-to-Date
 
Patricia Ganz
Leadership - Intrinsic LifeSciences (I)
Stock and Other Ownership Interests - Abbott Laboratories; Disc Medicine (I); Intrinsic LifeSciences (I); Johnson & Johnson; Merck; Novartis; Pfizer; Teva; xenon pharma (I)
Consulting or Advisory Role - Astellas Pharma; Chugai Pharma (I); Dexcel Pharma (I); Disc Medicine (I); InformedDNA; Ionis Pharmaceuticals (I); Silence Therapeutics (I)
Patents, Royalties, Other Intellectual Property - related to iron metabolism and the anemia of chronic disease (I); Up-to-Date royalties for section editor on survivorship
 
Charles Blanke
No Relationships to Disclose
 
Norman Wolmark
Research Funding - Breast Cancer Research Foundation (Inst)
Travel, Accommodations, Expenses - American Surgical Association
 
Michael Overman
Consulting or Advisory Role - 3T BioSciences; Agenus; Bristol-Myers Squibb; Eisai; Janssen; Merck; Pfizer; Roche/Genentech; Simcere; Summit Therapeutics
Research Funding - Bristol-Myers Squibb; MedImmune; Merck; Roche