The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase I, multicenter, first-in-human (FIH) global study of SIM0505, an anti-CDH6 (CDH6) antibody-drug conjugate (ADC) in patients with advanced solid tumors.
 
Xiaohua Wu
No Relationships to Disclose
 
Rujiao Liu
No Relationships to Disclose
 
Xiaowei Liu
No Relationships to Disclose
 
Yan Zhang
No Relationships to Disclose
 
Dihong Tang
No Relationships to Disclose
 
Shusuan Jiang
No Relationships to Disclose
 
Jundong Li
No Relationships to Disclose
 
Daruka Mahadevan
Honoraria - Caris Life Sciences; Guardant Health
Speakers' Bureau - Caris Life Sciences; Guardant Health
Travel, Accommodations, Expenses - Caris Life Sciences; Guardant Health
 
Cesar Augusto Perez
Consulting or Advisory Role - BeiGene; Ipsen; Pfizer
Research Funding - Accutar Biotech (Inst); ADANATE Biotechnology (Inst); Avenzo Therapeutics (Inst); Avenzo Therapeutics (Inst); BeiGene (Inst); Coherent Biopharma (Inst); Coherus Biosciences (Inst); Compass Therapeutics (Inst); Corvus Pharmaceuticals (Inst); DualityBio (Inst); Elevation Oncology (Inst); Exelixis (Inst); Genentech (Inst); Kura Oncology (Inst); Loxo/Lilly (Inst); Menarini (Inst); Merus (Inst); Mirati Therapeutics (Inst); NextCure (Inst); PDS Biotechnology (Inst); Pfizer (Inst); Pierre Fabre (Inst); Relay Therapeutics (Inst); Systimmune (Inst); Tachyon Therapeutics (Inst); Tallac Therapeutics (Inst); Torl Biotherapeutics (Inst); Xilio Therapeutics (Inst); Zhuhai Yufan Biotechnologies (Inst)
 
Beryl Manning-Geist
Consulting or Advisory Role - Caris Life Sciences; Incyclix Bio
 
Dmitriy Zamarin
Leadership - Accurius
Stock and Other Ownership Interests - Accurius; Calidi Biotherapeutics; ImmunOs Therapeutics; OverT
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Cytel; Daiichi Sankyo/Lilly; Everest Medicine; Gilead Sciences; Hervolution; Lilly; Memgen; Replimune; Takeda; Xencor
Research Funding - NextCure (Inst); Volastra Therapeutics (Inst); Xencor (Inst); Zymeworks (Inst)
Patents, Royalties, Other Intellectual Property - I hold a patent regarding the use of recombinant Newcastle Disease Virus (NDV) for cancer therapy. (Inst)
(OPTIONAL) Uncompensated Relationships - BioCanRx; Kalivir Immunotherapeutics; Oncolys BioPharma
 
Miguel Gonzalez-Velez
No Relationships to Disclose
 
Sarah Premji
No Relationships to Disclose
 
Hongxia Wang
No Relationships to Disclose
 
Jiajia Li
No Relationships to Disclose
 
Rong Sun
Employment - Shanghai Simcere Zaiming Biotechnology Co., Ltd
 
Qi Fu
Employment - Zaiming
 
Haolin Sun
Employment - Simcere
Leadership - Simcere
Stock and Other Ownership Interests - Simcere
 
Ashley Martz
Employment - NextCure
Stock and Other Ownership Interests - NextCure
 
Udayan Guha
Employment - NextCure Inc.; TCR2 Therapeutics
Leadership - Grannus Therapeutics
Stock and Other Ownership Interests - NextCure; TCR2 Therapeutics