The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Immunologic determinants in procured melanoma tissue as drivers of durable response to tumor-infiltrating lymphocyte therapy.
 
Lilit Karapetyan
Research Funding - Iovance Biotherapeutics (Inst); Valar Labs (Inst)
Travel, Accommodations, Expenses - immatics
 
Jin Xu
No Relationships to Disclose
 
Kimberly Ward
Research Funding - Iovance Biotherapeutics (Inst)
 
Denise Kalos
No Relationships to Disclose
 
Xiaofei Song
No Relationships to Disclose
 
Matthew Perez
Honoraria - Guidepoint Global; Replimune
Consulting or Advisory Role - Guidepoint Global; Replimune
 
John Mullinax
Consulting or Advisory Role - Iovance Biotherapeutics; Lyell Immunopharma; Merit Medical Systems
Research Funding - Intellia Therapeutics (Inst); Iovance Biotherapeutics (Inst)
Patents, Royalties, Other Intellectual Property - IP licensed to Iovance by my institution on which I am an inventor. (Inst)
 
Jonathan Zager
Stock and Other Ownership Interests - Johnson & Johnson/Janssen
Honoraria - Castle Biosciences; Delcath Systems; Merck; Merit Medical Systems; Skyline Diagnostics
Consulting or Advisory Role - Castle Biosciences; Delcath Systems; Philogen; Skyline Diagnostics
Speakers' Bureau - Merit Medical Systems; Skyline Diagnostics
Research Funding - Delcath Systems (Inst); Philogen (Inst)
Patents, Royalties, Other Intellectual Property - US Patent # 11,779,698; US Patent 10,583,246
Expert Testimony - Gideon Assen; Hinshaw Culbertson; McGowan, Hood, Felder & Phillips, LLC
Travel, Accommodations, Expenses - Merck
 
Vernon Sondak
Consulting or Advisory Role - Bristol-Myers Squibb; Merck/Schering Plough; Mural Oncology; Regeneron
Research Funding - Neogene Therapeutics (Inst); Skyline Diagnostics (Inst)
 
Kenneth Tsai
Consulting or Advisory Role - Sun BioPharma
 
Jane Messina
No Relationships to Disclose
 
Joseph Markowitz
Stock and Other Ownership Interests - Amdocs; Consolidated Edison
Consulting or Advisory Role - Newlink Genetics
Research Funding - Idera (Inst); Merck (Inst); Morphogenesis (Inst)
Patents, Royalties, Other Intellectual Property - Patent on development of Inhibitors for S100B (Inst); Pending patent on flow cytometry analysis system (Inst); Pending patent on the role of nitric oxide in melanoma. (Inst)
Other Relationship - Springer
 
Andrew Brohl
Consulting or Advisory Role - Deciphera
Research Funding - Merck (Inst)
 
Zeynep Eroglu
Consulting or Advisory Role - Natera; Pfizer; Regeneron; Replimune; Sun Pharma
Research Funding - Boehringer Ingelheim (Inst); Pfizer (Inst)
 
Ahmad Tarhini
Consulting or Advisory Role - AstraZeneca; Bayer; BioNTech; Bristol-Myers Squibb; Clinigen Group; ConcertAI; Eisai; Genentech/Roche; Instil Bio; Merck; Moderna Therapeutics; Nested; Novartis; Partner Therapeutics; Sanofi/Regeneron
Research Funding - Acrotech Biopharma (Inst); Agenus (Inst); Bristol-Myers Squibb (Inst); Clinigen Group (Inst); Dragonfly Therapeutics (Inst); Genentech/Roche (Inst); InflaRx (Inst); Merck (Inst); Nested Therapeutics (Inst); OncoResponse (Inst); OncoSec (Inst); Pfizer (Inst); Sanofi/Regeneron (Inst); Scholar Rock (Inst); Werewolf Therapeutics (Inst)
 
Nikhil Khushalani
Stock and Other Ownership Interests - Bellicum Pharmaceuticals
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Castle Biosciences; Delcath Systems; Immunocore; Incyte; Instil Bio; IO Biotech; Iovance Biotherapeutics; Merck; Mural Oncology; Nektar; Novartis; Regeneron; Replimune; Sun Pharma
Research Funding - BioNTech SE (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); HUYA Bioscience International (Inst); IDEAYA Biosciences (Inst); Merck (Inst); Modulation Therapeutics (Inst); Novartis (Inst); Regeneron (Inst); Replimune (Inst)
Travel, Accommodations, Expenses - Castle Biosciences; Regeneron
Other Relationship - Bristol-Myers Squibb/Celgene; Nektar; Regeneron; Replimune; Sun Pharma
(OPTIONAL) Uncompensated Relationships - T-Knife
 
James Mule
No Relationships to Disclose
 
Amod Sarnaik
Stock and Other Ownership Interests - Specicare
Honoraria - Blueprint Oncology; Gerson Lehrman Group; Guidepoint Inc; Iovance Biotherapeutics (Inst); Replimune; Society for Immunotherapy of Cancer
Consulting or Advisory Role - Iovance Biotherapeutics
Research Funding - Genentech (Inst); Iovance Biotherapeutics (Inst); Provectus (Inst); Turnstone Bio (Inst)
Patents, Royalties, Other Intellectual Property - Compositions and methods for improving tumor-infiltrating lymphocytes for adoptive cell therapy, filed March 20, 2014 U.S. Patent Application No. 61/955,970 and second Application No. 61/973,002 (Inst); Culture of Tumor-infiltrating lymphocytes from tumor digest, filed March 24, 2021 US Patent Application No. 17/279,327 (Inst); Method of ex vivo enhancement of immune cell activity for cancer immunotherapy with a small molecule ablative compound, filed August 21, 2018 U.S. Patent Application No. 14/974,357; Rapid method for culture of tumor-infiltrating lymphocytes from core needle biopsies of solid tumors, filed January 2, 2018 U.S. Patent Application No. 62/612,915 (Inst); Tumor-infiltrating lymphocytes and stapled peptoid peptide hybrid peptidomimetics, filed October 11, 2018 U.S. Patent Application No. 16/157,174 (Inst)
Travel, Accommodations, Expenses - Bluprint Oncology Concepts
 
Matthew Beatty
Consulting or Advisory Role - TuHura Biosciences
Research Funding - Turnstone Bio (Inst)
 
Shari Pilon-Thomas
Consulting or Advisory Role - KSQ Therapeutics; Morphogenesis, Inc.
Research Funding - Celgene/Bristol-Myers Squibb (Inst); Dyve Bioscience (Inst); Intellia Therapeutics (Inst); Iovance Biotherapeutics (Inst); Provectus (Inst); Turnstone Bio (Inst)
Patents, Royalties, Other Intellectual Property - IP licensed from Moffitt to Tuhura. (Inst); Moffitt Cancer Center has licensed Intellectual Property related to the proliferation and expansion of tumor infiltrating lymphocytes (TILs) to Iovance Biotherapeutics. Shari Pilon-Thomas is an inventor on such Intellectual Property. (Inst); Patent with Provectus (Inst)