The following represents disclosure information provided by authors of this abstract. The ASCO Scientific Program Committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered self-held and compensated unless otherwise noted. Employment/Leadership relationships are considered compensated employment unless otherwise noted. L = Leadership, U = Uncompensated, I = Immediate Family Member, B = Both Myself and Immediate Family Member, Inst = My Institution
METRIC phase III study: Efficacy of trametinib (T), a potent and selective MEK inhibitor (MEKi), in progression-free survival (PFS) and overall survival (OS), compared with chemotherapy (C) in patients (pts) with BRAFV600E/K mutant advanced or metastatic melanoma (MM).
Caroline Robert
Consultant or Advisory Role - Bristol-Myers Squibb; GlaxoSmithKline; Roche
Keith T. Flaherty
Consultant or Advisory Role - GlaxoSmithKline
Peter Hersey
No relevant relationships to disclose
Paul D. Nathan
Consultant or Advisory Role - GlaxoSmithKline
Honoraria - GlaxoSmithKline
Claus Garbe
Consultant or Advisory Role - Amgen; Bristol-Myers Squibb; Genta; GlaxoSmithKline; MSD; Philogen; Roche; Swedish Orphan SOBI
Honoraria - Bristol-Myers Squibb; MSD; Philogen; Roche; Swedish Orphan SOBI
Research Funding - Bristol-Myers Squibb; Genta; MSD; Roche; SOBI
Mohammed M. Milhem
No relevant relationships to disclose
Lev V. Demidov
Honoraria - GlaxoSmithKline; MSD
Research Funding - Bristol-Myers Squibb; GlaxoSmithKline; Pfizer; Roche
Jessica C. Hassel
Consultant or Advisory Role - GlaxoSmithKline
Research Funding - GlaxoSmithKline
Piotr Rutkowski
Consultant or Advisory Role - Bristol-Myers Squibb; Novartis
Honoraria - Bristol-Myers Squibb (B); GlaxoSmithKline; MSD; Novartis; Pfizer
Peter Mohr
No relevant relationships to disclose
Reinhard Dummer
Consultant or Advisory Role - GlaxoSmithKline
Honoraria - GlaxoSmithKline
Research Funding - GlaxoSmithKline
Uwe Trefzer
Consultant or Advisory Role - GlaxoSmithKline
James M. G. Larkin
Consultant or Advisory Role - GlaxoSmithKline
Jochen Utikal
Honoraria - GlaxoSmithKline
Michelle Casey
Employment or Leadership Position - GlaxoSmithKline
Stock Ownership - GlaxoSmithKline
Laurie Jill Sherman
Employment or Leadership Position - GlaxoSmithKline
Stock Ownership - GlaxoSmithKline
Wendy A. Crist
Employment or Leadership Position - GlaxoSmithKline
Frank S. Wu
Employment or Leadership Position - GlaxoSmithKline
Stock Ownership - GlaxoSmithKline
Kiran Patel
Employment or Leadership Position - GlaxoSmithKline
Stock Ownership - GlaxoSmithKline
Dirk Schadendorf
Consultant or Advisory Role - GlaxoSmithKline
Honoraria - GlaxoSmithKline